Pubblicazioni

Colorectal cancer. Epidemiology, etiology, pathogenesis and prevention.

28 April 1995

Colorectal cancer. Epidemiology, etiology, pathogenesis and prevention.


Crucitti F, Sofo L, Ratto C, Merico M, Ippoliti M, Crucitti P, Doglietto GB.

Rays. 1995 Apr-Jun;20(2):121-31.

Colorectal cancer (CRC) is a neoplasm with a steadily growing incidence in Western countries. Moreover the age of 50 and over is a critical risk factor. The relationship between dietary, environmental factors and CRC has been evaluated. At present, a number of genetic risk factors such as the genetic susceptibility, tumor suppressor genes and oncogenes are thought to play a major role. The correlation of CRC with adenomatous polyps and chronic inflammatory disease, ulcerative colitis in particular, has been evaluated. Prevention of CRC is mainly based on a rational diet and in the adoption of mass screening programmes.

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